- #Jasco spectra manager circular dichroism 64 Bit#
- #Jasco spectra manager circular dichroism software#
- #Jasco spectra manager circular dichroism Pc#
Patel RP, Narkowicz C, Hutchinson JP, Hilder EF, Jacobson GA (2008) J Pharm Biomed Anal 46:30–35 Trehy ML, Reepmeyer JC, Kolinski RE, Westenberger BJ, Buhse LF (2009) J Pharm Biomed Anal 49:670–673 118 (2008), Information Exchange System, World Health Organization, Geneva, Switzerland. Kishimoto TK, Viswanathan K, Ganguly T, Elankumaran S, Smith S, Pelzer K, Lansing JC, Sriranganathan N, Zhao G, Galcheva-Gargova Z, Al-Hakim A, Bailey GS, Fraser B, Roy S, Rogers-Cotrone T, Buhse L, Whary M, Fox J, Nasr M, Dal Pan GJ, Shriver Z, Langer RS, Venkataraman G, Austen KF, Woodcock J, Sasisekharan R (2008) New Engl J Med 358:2457–2467 Guerrini M, Beccati D, Shriver Z, Naggi A, Viswanathan K, Bisio A, Capila I, Lansing JC, Guglieri S, Fraser B, Al-Hakim A, Gunay NS, Zhang Z, Robinson L, Buhse L, Nasr M, Woodcock J, Langer R, Venkataraman G, Linhardt RJ, Casu B, Torri G, Sasisekharan R (2008) Nat Biotechnol 26:669–675 Lever R, Page CP (2002) Nat Rev Drug Discov 1:140–148 To the best of our knowledge, the findings presented here are the first report of heparin purity screening using traditional spectropolarimetry techniques. This strategy exploits the subtle differences in the optical properties of each polymer these differences result from structural dissimilarities. In this work, we report the use of circular dichroism spectroscopy to analyze heparin samples for the presence of heparin-like adulterants (e.g., chondroitin sulfate A, dermatan sulfate, and oversulfated chondroitin sulfate) in a simple and straightforward manner. These events highlighted the need for new, convenient heparin-screening methods capable of rapidly determining sample purity. Extensive investigations ultimately showed oversulfated chondroitin sulfate, a semi-synthetic polysaccharide, to be present in the contaminated samples. Recently, however, tainted heparin was associated with acute reactions that lead to numerous deaths. All prices in Euro, excluding VAT.Heparin, a heterogeneous polysaccharide, is used extensively as an anticoagulant.
#Jasco spectra manager circular dichroism Pc#
The interface to the PC is simple a USB port allowing the PC to change easily in the future as new operating systems evolve.Īll rights reserved. Spectra Manager CFR is available for laboratories falling under the FDA mandate 21CFR11.
Thermal analysis functions include determination of Tm, enthalpy and entropy and a protein-ligand binding calculation program is available for use with the titration system. Analysis functions designed for CD data include integrated algorithms for Secondary Structure Analysis and conversion of various Optical Constant units. User customizable toolbars are provided for frequently used functions. Measurement parameters are easy to store and retrieve for frequent measurements and a Macro command module allows automation of complex measurements including analysis and even printing to pre-set templates in the Canvas module. Optimized for multi-user environments Spectra Manager II can be very simple to operate but still offer the flexibility required for complex experiments.
#Jasco spectra manager circular dichroism 64 Bit#
Spectra Manager II is a 64 bit program designed for Windows 7 and is a complete suite offering data acquisition, analysis and presentation in Canvas a publication quality printing and display module.
#Jasco spectra manager circular dichroism software#
The new Jasco J-1000 Series utilizes the Spectra Manager II Spectroscopy Software Suite that is common with all other Jasco spectroscopy instrumentation.
0 kommentar(er)
